Hepatitis A is an acute (short-term but quite severe) infection of the liver caused by the hepatitis A virus. The hepatitis A virus can survive in the environment on hands for several hours and in food kept at room temperature for considerably longer and is relatively resistant to detergents. Hepatitis A occurs worldwide. In developing countries most people are infected during childhood due to poor sanitation. With good sanitation and hygiene in the developed world, most people now reach adulthood without being exposed to hepatitis A virus. VIVAXIM® is a vaccine used to help prevent Typhoid fever and Hepatitis A disease in adults over the age of 16 years who are at risk of these diseases. For long term protection against infection with hepatitis A virus you should obtain a booster dose of AVAXIM ® (hepatitis A vaccine) 6-36 months after your dose of VIVAXIM®. You should be revaccinated against Typhoid fever, every 3 years. VIVAXIM® may have unwanted side effects in a few people. All medicines, including vaccines, can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects. Ask your doctor or pharmacist to answer any questions you may have. Tell your doctor or pharmacist if you notice any of the following and they worry you: • Local reaction around the injection site such as redness, pain, swelling or hardness • Headaches • Generally feeling unwell • Soreness, aching muscles, muscle tenderness or weakness (not caused by exercise) • Nausea or diarrhoea • Fever. sanofi-aventis

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