Japanese encephalitis is a viral infection transmitted by mosquitoes. Although most infections are asymptomatic, symptomatic infection is often serious and can lead to neurological sequelae or death. The virus has been found throughout Asia and Papua New Guinea and vaccination is indicated for adults who live in or travel to these endemic areas, or who work with the virus in laboratories. Approx 40% of subjects experience adverse reactions to IXIARO®/JESPECT®, they usually occur in the first 3 days following vaccination. Side effects are usually mild and only in the first few days. Most commonly reported were: 26% headaches 21% aches and pains 13% flu like illness 13% fatigue Valneva

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